Planar Polarity: Converting a Morphogen Gradient into Cellular Polarity
نویسندگان
چکیده
Epithelial cells are polarized within the apico-basal and planar axes. The latter - planar cell polarity - requires long-range regulation of orientation as well as short-range, cell-to-cell realignment through feedback loops. New insights into the long-range, gradient-type regulation reveal how a kinase translates the morphogen gradient input into cellular orientation.
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ورودعنوان ژورنال:
- Current Biology
دوره 25 شماره
صفحات -
تاریخ انتشار 2015